Oh dear. Well, It didn’t think I’d have cause to write about methamphetamine production again, but here we are. Many readers will have heard news about the explosion that rocked the NIST lab near Washington, D.C. back in July. Luckily, no one was seriously injured; but one security guard did sustain some burns.
No more than a couple days later, initial investigations revealed the cause of the explosion appeared to be… methamphetamine synthesis. Now, any competent chemist in a national lab would (hopefully) be able to perform any of the common meth syntheses without incident. Certainly without blowing the windows out of the building and hospitalizing his or herself.
But as it turns out, the culprit wasn’t a chemist, but the security guard injured in the blast. More details have been emerging since the incident. After resigning from the force, the guard in question pled guilty to attempted methamphetamine manufacture.
It turns out the method the guard was attempting to employ is that known colloquially as the “Shake and Bake” method. This involves reduction of pseudoephedrine to methamphetamine, then treatment of the reaction mixture with hydrochloric acid, forming a salt which is easily separated. And in true MacGyver style, the reagents used in this reduction are all improvised: camping stove fuel as a solvent, lithium from batteries, lye, and ammonium nitrate (fertilizer). HCl is generated by the action of sulfuric acid (sold as drain cleaner) on table salt. Literally everything you need can be purchased at Wal-Mart.
And what do we do with these reagents? Why, toss them in a water bottle, close the cap, and shake, of course. You can’t hear it, but I’m actually screaming behind my keyboard.
The idea is you vent the bottle, as a good amount of gas is going to come off of that particular reaction. The reason people use this method to make meth, aside from easy access to the starting materials, is that it can be done on a very small scale: a few grams.
What I don’t understand is why, if you’re going to illicitly make methamphetamine in a synthetic chemistry lab, you decide to bypass all those fancy solvents, reagents, glassware, and safety equipment. Maybe they were worried someone was taking inventory of the reagents they’d need? In my experience, it’s highly unlikely anyone was.
Instead of doing some homework and using the lab equipment that was already right there, they opted to go straight to the basement-bottom chemistry.
And again, I can only speculate as to exactly what caused the explosion (chemists: take your pick of things that could go wrong with that procedure), but I’d put money on overpressure in the “reaction vessel,” resulting in rupture, and exposure of lithium to air. That would likely generate enough heat to ignite the expanding camp-fuel-solvent cloud. And ka-boom.
I’ll take “Syntheses I won’t attempt” for 500, Alex.